A mild intravascular hemolytic anemia resulting from forceful ...

[Mimi]

A mild intravascular hemolytic anemia resulting from forceful repeated effect of the feet on hard surfaces is called:
 
  a. Traumatic cardiac hemolytic anemia
  b. Exercise-induced hemoglobinuria
  c. Bartonellosis
  d. Thrombotic thrombocytopenic purpura

Question 2

What is the pathogenesis of MAHA?
 
  a. Microthrombi and fibrin formed on damaged endothelial cells trap and break red cells.
  b. Chemicals or heat destroy red blood cells (RBCs).
  c. The spleen sequesters red cells in an attempt to remove abnormal inclusions.
  d. Antibodies that activate complement are formed and destroy the red cell membrane.

[Christopher]

Answer to Question 1

ANS: B
Exercise-induced hemoglobinuria occurs in some individuals after repeated forceful effect of the feet on hard surfaces. This also may be called March hemoglobinuria.

Answer to Question 2

ANS: A
As red cells pass through fibrin deposits that have been abnormally formed inside the lumen of blood vessels, they are fragmented as the force of blood flow forces them through the fibrin. Red cell fragments may also be formed by turbulence of red cells as they pass over damaged endothelial cells that line the blood vessels.

[Mimi]

Gracias!

[frankwu0507]

Thanks for the timely response, appreciate it