A patient has been diagnosed with anemia. The physician suspects ...

[panfilo]

A patient has been diagnosed with anemia. The physician suspects an immune hemolytic anemia and orders a Coombs test. The patient asks the nurse what this test will tell the doctor. The nurse replies,
 
  A)
  They will wash your RBCs and then mix the cells with a reagent to see if they clump together.
  B)
  They will look at your RBCs under a microscope to see if they have an irregular shape (poikilocytosis).
  C)
  They will be looking to see if you have enough ferritin in your blood.
  D)
  They are looking for the presence of antibody or complement on the surface of the RBC.

Question 2

Following an injury resulting in a small cut from a knife, the first cells to go to the area of the cut would be the
 
  A)
  neutrophils.
  B)
  erythrocytes.
  C)
  albumin.
  D)
  basophils.

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Answer to Question 1

Ans:
D

Feedback:

The Coombs test is used to diagnose immune hemolytic anemias. It detects the presence of antibody or complement on the surface of the red cell. Answer choice A refers to direct antiglobulin test (DAT). Answer choice B refers to blood smear test. Answer choice C refers to iron stores test.

Answer to Question 2

Ans:
A

Feedback:

Neutrophils are very mobile and are the first cells to go to an area of tissue damage. Erythrocytes (RBCs) contain an O2-carrying protein that functions in the transport of oxygen. Albumin, a plasma protein, does not pass through the pores in the capillary wall to enter the interstitial fluid and therefore contributes to the plasma osmotic pressure and maintenance of blood volume. Basophil granules contain heparin, an anticoagulant; histamine, a vasodilator; and other mediators of inflammation.

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