All of the following are examples of microangiopathic hemolytic ...

[roselinechinyere27m]

All of the following are examples of microangiopathic hemolytic anemias (MAHAs) except:
 
  a. Thrombotic thrombocytopenia purpura
  b. Hemolytic uremic syndrome
  c. Disseminated intravascular coagulation (DIC)
  d. Immune thrombocytopenia purpura

Question 2

Paroxysmal nocturnal hemoglobinuria is:
 
  a. Inherited as an X-linked recessive trait
  b. Acquired as a clonal disorder
  c. Inherited as an autosomal dominant disorder
  d. Acquired after a viral infection

[vickybb89]

Answer to Question 1

ANS: D
Thrombotic thrombocytopenia purpura, hemolytic uremic syndrome, and DIC are all examples of MAHAs. An antibody against platelets causes immune thrombocytopenia purpura, and only the platelet count is affected. No anemia exists unless the patient is bleeding because of the low platelet count; if the bleeding is occult, then this eventually could result in iron deficiency anemia but not MAHA.

Answer to Question 2

ANS: B
Paroxysmal nocturnal hemoglobinuria is an acquired disorder that can be shown to be clonal in nature. Some patients have two populations of red cells: (1) normal and (2) defective.

[roselinechinyere27m]

Thanks for the timely response, appreciate it

[bulacsom]

Wow, this really help