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Author Question: Why is heme located inside a globin chain pocket surrounded by hydrophobic amino acids? a. ... (Read 51 times)

genevieve1028

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on: Jun 25, 2018
Why is heme located inside a globin chain pocket surrounded by hydrophobic amino acids?
 
  a. Protects iron from being oxidized to its ferric form
  b. Necessary for oxygen release to tissues
  c. Makes hemoglobin insoluble
  d. Keeps heme from being dissolved

Question 2

Where is heme produced?
 
  a. Liver
  b. Macrophages in the bone marrow
  c. Red blood cell (RBC) precursors in the bone marrow
  d. Mature RBCs in peripheral circulation


kusterl

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: A
This arrangement helps keep iron in the divalent (ferrous) form regardless of whether or not it is carrying oxygen. This is critical for hemoglobin's ability to reversibly bind oxygen.

Answer to Question 2

ANS: C
Heme is produced in RBC precursors in the bone marrow.


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