A 64-year-old patient received an SCT in March. Two weeks after ...

[deesands]

A 64-year-old patient received an SCT in March. Two weeks after the transplant, the physician ordered a routine blood count. The patient's ANC is 12 x109/L, and his platelet count is 65 x 109/L.
 
  Chimerism studies were performed 6 months after his transplant using VNTR polymorphisms, which indicated a partial chimerism. Interpret these results regarding what they mean for the patient.
 
  a. The patient achieved short-term and long-term engraftment.
  b. The patient achieved long-term engraftment but not short-term engraftment.
  c. The patient achieved short-term engraftment, but long-term results are indeterminate.
  d. The patient did not achieve engraftment at all.

Question 2

Which HSC quantitation method would be optimal for verification of late-stage engraftment?
 
  a. Manual count of MNCs
  b. CD34 enumeration by flow cytometry
  c. Cell culture for CFUs
  d. Bone marrow exam for stem cells

[Edwyer]

Answer to Question 1

Correct Answer: C

Answer to Question 2

Correct Answer: C

[deesands]

Excellent

[mjenn52]

TYSM