A 53-year-old female hospital patient has received a kidney ...

[lindiwe]

A 53-year-old female hospital patient has received a kidney transplant following renal failure secondary to hypertension.
 
  As part of the teaching while she was on the organ wait list, she was made aware that she would need to take antirejection drugs for the rest of her life. Which aspect of the immune system underlies this necessity?
  A)
  The lack of identifiable major histocompatibility complex (MHC) molecules will stimulate the innate immune response.
  B)
  Donor organ antibodies will be identified as foreign and stimulate an immune response.
  C)
  Antirejection drugs will stimulate the production of familiar MHC molecules.
  D)
  MHC molecules will never develop in the cells of the donor organ, and effector cells will be continually stimulated.

Question 2

Members of an AIDS support group who have more advanced cases are sharing some of their recent health problems with a member who has just been diagnosed. Which of the member's statements is most accurate?
 
  A)
  One of the scariest things out there now is the huge increase in drug-resistant tuberculosis.
  B)
  The eradication of Pneumocystis jiroveci pneumonia (PCP) has helped extend the life expectancy of a lot of persons living with AIDS.
  C)
  Those of us with HIV are so much more prone to loss of vision and hearing.
  D)
  As people with HIV live longer, most of us are eventually succumbing to the cancers that are associated with HIV.

[kiamars2010]

Answer to Question 1

Ans:
D

Feedback:

The lack of familiar MHC molecules will stimulate an immune response by effector cells in the absence of antirejection drugs. An innate immune response is not central to the response, but rather the adaptive immune system. Lack of known MHC molecules, not foreign antibodies, accounts for the immune response, and familiar MHC molecules will not be produced by the donor kidney cells.

Answer to Question 2

Ans:
D

Feedback:

There is an increased risk of AIDS-associated cancers as persons with age live longer. Drug resistance in tuberculosis is on the decline in recent years, and PCP has not been eradicated. Sensory loss is not a noted HIV-related manifestation.

[lindiwe]

Excellent

[juliaf]

TYSM