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Author Question: Explain how ALL and Burkitt-type ALL are different morphologically. What will be an ideal ... (Read 46 times)

erika

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on: Jun 25, 2018
Explain how ALL and Burkitt-type ALL are different morphologically.
 
  What will be an ideal response?

Question 2

Explain the major differences between Hodgkin and non-Hodgkin lymphomas.
 
  What will be an ideal response?


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javimendoza7

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer:
ALL: Burkitt-type ALL
1. Small or large, homogeneous: Large/heterogeneous
2. Nuclear chromatin: fine or clumped: Nuclear chromatin: fine and homogeneous
to variable
3. Nuclear shape: occasional clefting: Nuclear shape: regular, oval to round
or indentation
4. Nucleoli: not visible to large and prominent: Nucleoli: prominent, one or more
5. Cytoplasm: scanty or abundant: Cytoplasm: moderately abundant
6. Basophilia: variable: Basophilia: very deep
7. Vacuolization: variable: Vacuolization: often prominent

Answer to Question 2

Answer: Hodgkin lymphoma:
 Stage: localized
 Distribution: central nodes
 Mode of spread: contiguous
 Extranodal disease: uncommon
 PB: never involved
 Cell type: abnormal bizarre cells
 Treatment regimen: often ABVD

Non-Hodgkin lymphoma:
 Stage: widespread
Distribution: peripheral nodes
 Mode of spread: noncontiguous
 Extranodal disease: common
 PB: can be involved
 Cell type: resembles normal lymphoid cells
 Treatment regimen: often CHOP


erika

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

sultansheikh

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Reply 3 on: Yesterday
Gracias!

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