« previous next »

Author Question: Explain the molecular and cytogenetic profile of a patient with Burkitt lymphoma. What will be an ... (Read 67 times)

silviawilliams41

  • Hero Member
  • *****
  • Posts: 560
on: Jun 25, 2018
Explain the molecular and cytogenetic profile of a patient with Burkitt lymphoma.
 
  What will be an ideal response?

Question 2

Morphological differences between ALL and Burkitt-type ALL include which of the following?
 
  a. Cell size, nuclear shape, and nuclear chromatin
  b. Cell size, cytoplasmic basophilia, and cellular heterogeneity
  c. Nucleoli, cytoplasmic volume, and vacuolation
  d. Cell size, cytoplasmic basophilia and vacuolation, and prominent nucleoli


kilada

  • Sr. Member
  • ****
  • Posts: 311
Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer:
Cytogenetic: Translocation of the MYC gene (8q24) to the heavy chain region on chromosome 14 (t(8,14)) or to light chain loci on chromosome 2p12 (t(2,8))
Molecular profile: clonal rearrangement of immunoglobulin heavy and light chain genes

Answer to Question 2

Correct Answer: D


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
« previous next »
 

Did you know?

Over time, chronic hepatitis B virus and hepatitis C virus infections can progress to advanced liver disease, liver failure, and hepatocellular carcinoma. Unlike other forms, more than 80% of hepatitis C infections become chronic and lead to liver disease. When combined with hepatitis B, hepatitis C now accounts for 75% percent of all cases of liver disease around the world. Liver failure caused by hepatitis C is now leading cause of liver transplants in the United States.

Did you know?

Though “Krazy Glue” or “Super Glue” has the ability to seal small wounds, it is not recommended for this purpose since it contains many substances that should not enter the body through the skin, and may be harmful.

Did you know?

Only one in 10 cancer deaths is caused by the primary tumor. The vast majority of cancer mortality is caused by cells breaking away from the main tumor and metastasizing to other parts of the body, such as the brain, bones, or liver.

Did you know?

Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.

Did you know?

It is difficult to obtain enough calcium without consuming milk or other dairy foods.

Proper placement and monitoring of an automatic blood pressure cuff will reduce the risk of injury o Proper placement and monitoring of an automatic blood pressure cuff will reduce the risk of injury o
Measuring Patient Height Measuring Patient Height
Electrocardiography. (a) Electrodes are placed on the patient’s chest to record the electrical event Electrocardiography. (a) Electrodes are placed on the patient’s chest to record the electrical event
Patient teaching: female breast assessment Patient teaching: female breast assessment
Koplik spots in the mouth of a patient with measles. Koplik spots in the mouth of a patient with measles.
Please fully explain the answer with steps Please fully explain the answer with steps
Video: Electrical Conduction System of the Heart

For a complete list of videos, visit our video library