This topic contains a solution. Click here to go to the answer

Author Question: A laboratory professional is reviewing a peripheral blood smear of a 10-year-old patient and notes ... (Read 159 times)

abern

  • Hero Member
  • *****
  • Posts: 533
A laboratory professional is reviewing a peripheral blood smear of a 10-year-old patient and notes that 35 blasts are present. Which of the following diagnoses is likely based on these findings?
 
  a. Myelodysplastic syndrome
  b. Acute leukemia
  c. Chronic myeloid leukemia
  d. Aplastic anemia

Question 2

A 61-year-old woman saw her primary care physician because of fatigue and dyspnea on exertion for the past 3 months.
 
  Past medical history noted that the patient had been treated 5 years earlier with the DNA alkylating agent cyclophosphamide, non-Hodgkin lymphoma.
 
  A CBC revealed the following:
  WBC: 3.6 x 109/L
  RBC: 2.8 x 1012/L
  Hb: 9.1 g/dL
  MCV: 104 fL
  Reticulocyte count: 2.0
  Normal vitamin B12 and folic acid levels
  PLT: 120 x 109/L
  Differential: 6 blasts
 
  A bone marrow biopsy revealed hypercellularity, and dyshematopoiesis of all three myeloid lineages.
  Suggest an appropriate follow-up test and a likely diagnosis for this patient.
 
  What will be an ideal response?



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

meltdown117

  • Sr. Member
  • ****
  • Posts: 326
Answer to Question 1

Correct Answer: B

Answer to Question 2

Answer: Cytogenetics would be an appropriate follow-up test and would likely reveal a complex karyotype. The likely diagnosis is therapy-related myelodysplasia indicated because of the earlier treatment with cyclophosphamide and the trilineage cytopenias and dysplasia.




abern

  • Member
  • Posts: 533
Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it


kswal303

  • Member
  • Posts: 316
Reply 3 on: Yesterday
Gracias!

 

Did you know?

The top 10 most important tips that will help you grow old gracefully include (1) quit smoking, (2) keep your weight down, (3) take supplements, (4) skip a meal each day or fast 1 day per week, (5) get a pet, (6) get medical help for chronic pain, (7) walk regularly, (8) reduce arguments, (9) put live plants in your living space, and (10) do some weight training.

Did you know?

The first-known contraceptive was crocodile dung, used in Egypt in 2000 BC. Condoms were also reportedly used, made of animal bladders or intestines.

Did you know?

The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.

Did you know?

The liver is the only organ that has the ability to regenerate itself after certain types of damage. As much as 25% of the liver can be removed, and it will still regenerate back to its original shape and size. However, the liver cannot regenerate after severe damage caused by alcohol.

Did you know?

Critical care patients are twice as likely to receive the wrong medication. Of these errors, 20% are life-threatening, and 42% require additional life-sustaining treatments.

For a complete list of videos, visit our video library