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Author Question: Why are echinocytes seen in PK deficiency? What will be an ideal ... (Read 23 times)

imanialler

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on: Jun 25, 2018
Why are echinocytes seen in PK deficiency?
 
  What will be an ideal response?

Question 2

Female heterozygotes for G6PD deficiency have one population of cells that is normal and one that is G6PD deficient because:
 
  a. There is random inactivation of one X chromosome
  b. There is random inactivation of one Y chromosome.
  c. There is random activation of one X chromosome.
  d. There is random activation of one Y chromosome.


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smrerig

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: PK deficiency impairs the production of ADP. This impairment alters the erythrocyte membrane and causes excessive efflux of potassium and influx of calcium and sodium, which dehydrates the RBC, forming spiculed RBCs.

Answer to Question 2

Correct answer: A


imanialler

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Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)

upturnedfurball

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Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

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