Author Question: An apparent pancytopenia is noted in a patient's CBC results. A bone marrow aspirate is performed, ... (Read 75 times)

tth

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An apparent pancytopenia is noted in a patient's CBC results. A bone marrow aspirate is performed, and the M:E results are 2:1. Do these results make sense? Why or why not?
 
  What will be an ideal response?

Question 2

Patient results indicate an RPI of 1.8 and an MCV of 109 fl. Do these results make sense? Why or why not?
 
  What will be an ideal response?



dlook33

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Answer to Question 1

Answer: Yes, these results make sense. The M:E ratio examines the relationship between myeloid and erythroid cells. The pancytopenia describes the overall number of cells present.

Answer to Question 2

Yes, these results make sense. This is the classic picture of a megaloblastic patient. Ineffective erythropoiesis is the result of abnormal division of erythroblastic precursors, and a macrocytic MCV is often the result of an absence of folate and Vitamin B12, which are essential proteins in DNA replication.



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