Author Question: List and explain the steps that neutrophils take to leave the peripheral blood circulation and lead ... (Read 53 times)

sarasara · **on:** Jun 25, 2018

List and explain the steps that neutrophils take to leave the peripheral blood circulation and lead to the neutrophil kill function.

What will be an ideal response?

Question 2

Leukocyte surface markers identify cell lineage and are helpful in differentiating neoplastic hematologic disorders. What is one method used to identify these surface markers?

a. Chamber counts
b. Leukocyte differential
c. Cytogenetic methods
d. Flow cytometry

Melissahxx · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

Answer: Step 1: Antigen causes the release of chemoattractants to draw neutrophils to it. Neutrophils diapedese from the marginal pool in blood vessels into the tissues toward the antigen (chemotaxis).
Step 2: Antigen is opsonized with antibodies produced by B lymphocytes so that the PMNs can recognize them.
Step 3: The PMN engulfs the foreign antigen to form a phagosome.
Step 4: The PMN granules fuse with the phagosome (phagolysosome) and chemically digest it.

Answer to Question 2

Correct Answer: D