A patient is having difficulty achieving adequate anticoagulation ...

[NguyenJ]

A patient is having difficulty achieving adequate anticoagulation with prescribed doses of warfarin. The nurse realizes that what might be indicated for this patient?
 
  1. genetic testing to determine if the patient metabolizes warfarin slower
  2. use of a different anticoagulant
  3. review of the patient's diet
  4. analysis of the patient's lifestyle

Question 2

Through genetic testing, a patient learns that he has an apolipoprotein E2 gene. What should this information suggest to the nurse?
 
  1. The patient is at reduced risk for developing Alzheimer disease.
  2. The patient is at increased risk for developing Alzheimer disease.
  3. The patient is at risk for contracting malaria.
  4. The patient is at risk for developing colorectal cancer.

[abctaiwan]

Answer to Question 1

Correct Answer: 1

One use of genetic testing involves predicting or studying the patient's response to particular medications. Pharmacogenetic testing has shown that 20 of Caucasians metabolize warfarin more slowly and take longer to achieve therapeutic dosing. Genetic testing could help determine why the patient has not achieved successful anticoagulation. There might not be another anticoagulant available for the patient. Reviewing the patient's diet might provide some information regarding dietary reasons for the unsuccessful anticoagulation of the patient. An analysis of the patient's lifestyle will not help determine why the patient has not been achieved successful anticoagulation.

Answer to Question 2

Correct Answer: 1

The apolipoprotein E gene provides instructions to make a protein that combines with fats in the body to form molecules called lipoproteins which are responsible for packaging cholesterol and other fats and carrying them through the bloodstream. Research has shown that a person who inherits at least one E4 allele will have a greater chance of developing Alzheimer disease. Inheriting the E2 allele does not indicate that a person is more likely to develop Alzheimer disease. The apolipoprotein E gene is not a predictor for contracting malaria or developing colorectal cancer.

[NguyenJ]

Thank you

[abctaiwan]

Happy to help you