A possible cause of acquired aplastic anemia in children is: ...

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A possible cause of acquired aplastic anemia in children is:
 
  a. Drugs. c. Deficient diet.
  b. Injury. d. Congenital defect.

Question 2

Chelation therapy is begun on a child with -thalassemia major. The purpose of this therapy is to:
 
  a. Treat the disease. c. Decrease the risk of hypoxia.
  b. Eliminate excess iron. d. Manage nausea and vomiting.

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Answer to Question 1

ANS: A
Drugs such as chemotherapeutic agents and several antibiotics such as chloramphenicol can cause aplastic anemia. Fanconi syndrome is a primary form of the disorder, which is congenital/present-at-birth and not acquired after birth. Injury, deficient diet, and congenital defect are not causative agents in acquired aplastic anemia.

Answer to Question 2

ANS: B
A complication of the frequent blood transfusions in thalassemia is iron overload. Chelation therapy with deferoxamine (an iron-chelating agent) is given with oral supplements of vitamin C to increase iron excretion. Chelation therapy treats the side effects of disease management. Decreasing the risk of hypoxia and managing nausea and vomiting are not the purposes of chelation therapy.