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Of the estimated 2 million heroin users in the United States, 600,000–800,000 are considered hardcore addicts. Heroin addiction is considered to be one of the hardest addictions to recover from.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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Colchicine is a highly poisonous alkaloid originally extracted from a type of saffron plant that is used mainly to treat gout.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.