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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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Nitroglycerin is used to alleviate various heart-related conditions, and it is also the chief component of dynamite (but mixed in a solid clay base to stabilize it).
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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.