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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
Women are 50% to 75% more likely than men to experience an adverse drug reaction.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
Adults are resistant to the bacterium that causes Botulism. These bacteria thrive in honey – therefore, honey should never be given to infants since their immune systems are not yet resistant.