Author Question: Compared to normal levels, a shift in the HbO2 curve to the right has which of the following ... (Read 15 times)

mrsjacobs44 · **on:** Jul 16, 2018

Compared to normal levels, a shift in the HbO2 curve to the right has which of the following ef-fects?

1. The affinity of Hb for O2 decreases.
2. The Hb saturation for a given PO2 falls.
3. The Hb saturation for a given PO2 rises.
a. 1 only
b. 1 and 2 only
c. 2 and 3 only
d. 1, 2, and 3

Question 2

What is the effect of an elevated intracellular 2,3-DPG concentration?

a. Decreases the availability of O2 to the tis-sues.
b. Increases the affinity of Hb for O2.
c. Increases the availability of O2 to the tis-sues.
d. Shifts the HbO2 dissociation curve to the left.

kusterl · **Reply #1 on:** Jul 16, 2018

Answer to Question 1

ANS: B
As blood pH drops and the curve shifts to the right, the Hb saturation for a given PO2 falls de-creased Hb affinity for O2.

Answer to Question 2

ANS: C
Increased 2,3-DPG concentrations shift the HbO2 curve to the right, promoting O2 unloading.