Compared to normal levels, a shift in the HbO2 curve to the right ...

[mrsjacobs44]

Compared to normal levels, a shift in the HbO2 curve to the right has which of the following ef-fects?
 
  1. The affinity of Hb for O2 decreases.
  2. The Hb saturation for a given PO2 falls.
  3. The Hb saturation for a given PO2 rises.
  a. 1 only
  b. 1 and 2 only
  c. 2 and 3 only
  d. 1, 2, and 3

Question 2

What is the effect of an elevated intracellular 2,3-DPG concentration?
 
  a. Decreases the availability of O2 to the tis-sues.
  b. Increases the affinity of Hb for O2.
  c. Increases the availability of O2 to the tis-sues.
  d. Shifts the HbO2 dissociation curve to the left.

[kusterl]

Answer to Question 1

ANS: B
As blood pH drops and the curve shifts to the right, the Hb saturation for a given PO2 falls de-creased Hb affinity for O2.

Answer to Question 2

ANS: C
Increased 2,3-DPG concentrations shift the HbO2 curve to the right, promoting O2 unloading.

[mrsjacobs44]

Excellent

[mcarey591]

Thanks for the timely response, appreciate it