Author Question: Which of the following may be recommended to reduce bronchial inflammation in a 12-year-old child ... (Read 6 times)

hubes95 · **on:** Jul 16, 2018

Which of the following may be recommended to reduce bronchial inflammation in a 12-year-old child with cystic fibrosis?

a. High-dose ibuprofen
b. High-dose acetaminophen
c. High-dose naproxen
d. High-dose corticosteroids

Question 2

Which of the following would be recommended for the management of an adult with a severe flail chest?

1. Continuous positive airway pressure (CPAP)
2. Pain management
3. Mechanical ventilation
4. Positive end-expiratory pressure (PEEP)
a. 1, 2
b. 2, 3
c. 2, 3, 4
d. 1, 2, 3, 4

raenoj · **Reply #1 on:** Jul 16, 2018

Answer to Question 1

A
High-dose ibuprofen is recommended in children and young adolescents with mild CF who have good lung function (an FEV1 >60 predicted) and no contraindications (e.g., gastrointestinal bleeding or renal impairment). Ibuprofen has been shown to reduce bronchial inflammation without hindering bacterial clearanceresulting in the decline of the patient's FEV1 per yearwith no remarkable side effects except painless gastrointestinal bleeding in 1 to 2 of patients. High-dose ibuprofen is thought to work by decreasing neutrophil migration and inflammation in the lungs. The initiation of ibuprofen is not recommended after the age of 13 years.

Answer to Question 2

C
Appropriate pain management is needed with a flail chest injury. Mechanical ventilation with PEEP will stabilize the chest and provide ventilatory support.