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As many as 20% of Americans have been infected by the fungus known as Histoplasmosis. While most people are asymptomatic or only have slight symptoms, infection can progress to a rapid and potentially fatal superinfection.
The average adult has about 21 square feet of skin.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
Fatal fungal infections may be able to resist newer antifungal drugs. Globally, fungal infections are often fatal due to the lack of access to multiple antifungals, which may be required to be utilized in combination. Single antifungals may not be enough to stop a fungal infection from causing the death of a patient.