A CD4+ count has been prescribed for a child with human ...

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A CD4+ count has been prescribed for a child with human immunodeficiency virus (HIV) infection. The nurse has explained to the mother the purpose of the blood test.
 
  Which of the fol-lowing comments by the mother would indicate that further explanation is required for the moth-er to understand the purpose of the blood test? 1. The CD4+ count is used to determine the child's immune status.
  2. The CD4+ count identifies the specific diagnosis of HIV infection.
  3. The CD4+ count is used to identify the risk for disease progression.
  4. The CD4+ count identifies the need for Pneumocystis jiroveci pneumonia prophylaxis after 1 year of age.

Question 2

The client who has been diagnosed with cancer is to receive chemotherapy with both cisplatin (Platinol-AQ) and vincristine (Oncovin). The client asks the nurse why both medications must be given together.
 
  The nurse's response is based on the understanding that the purpose of using both medications is to: 1. Prevent the destruction of normal cells.
  2. Increase the destruction of tumor cells.
  3. Decrease the risk of the alopecia and stomatitis.
  4. Increase the likelihood of erythrocyte and leukocyte recovery.

[dominiqueenicolee]

Answer to Question 1

2

Rationale: CD4+ counts are used to assess a young child's immune status, risk for disease pro-gression, and need for P. jiroveci pneumonia prophylaxis after 1 year of age. These counts are measured at 1 and 3 months, every 3 months until the age of 2 years, and at least every 6 months thereafter. More frequent monitoring of CD4+ counts is indicated when P. jiroveci pneumonia prophylaxis and antiretroviral therapy are recommended. The CD4+ count is not diagnostic of HIV infection.

Answer to Question 2

2

Rationale: Cisplatin (Platinol-AQ) is an alkylating-like medication, and vincristine (Oncovin) is a vinca alkaloid. Alkylating medications are cell cycle phasenonspecific. Vinca alkaloids are cell cycle phasespecific and act on the M phase. Single-agent medication therapy seldom is used. Combinations of medications are used to increase the destruction of tumor cells.

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TYSM

[mohan]

Thanks for the timely response, appreciate it