Which statement is accurate regarding pharmacotherapy in the ...

[Coya19@aol.com]

Which statement is accurate regarding pharmacotherapy in the older adult?
 
  1. Increased body water can lead to a higher risk of drug toxicity.
  2. Plasma levels are increased, leading to a heightened drug response.
  3. Generally, drug doses should be increased due to prolonged drug metabolism.
  4. Drug absorption is slower due to increased gastric pH.

Question 2

Which of the following kinds of drugs would be most likely to enter breast milk?
 
  1. Ionized
  2. Lipid-soluble
  3. Water-soluble
  4. Bound to plasma protein

[Jevvish]

Answer to Question 1

Correct Answer: 4
Rationale: The elderly have an increase in gastric pH, which slows absorption. Plasma levels are lower, causing a diminished drug response. Body water is reduced, leading to a higher risk of drug toxicity. Generally, drug doses are reduced because of prolonged drug metabolism.

Answer to Question 2

Correct Answer: 2
Rationale: As with the placenta, drugs that are ionized, water-soluble, and bound to plasma protein are less likely to enter breast milk.

[Coya19@aol.com]

Thanks for the timely response, appreciate it

[Alyson.hiatt@yahoo.com]

Gracias!