A patient is receiving a sulfonamide drug for the first time as ...

[appyboo]

A patient is receiving a sulfonamide drug for the first time as part of the therapy for a urinary tract infection. Which of the following adverse effects is most likely to occur during the first few doses of this drug?
 
  a. Decreased urine output
  b. Increased blood pressure
  c. Hypothermia
  d. Hypersensitivity

Question 2

A patient with a urinary tract infection is also receiving anticoagulant therapy with warfarin. Which of the following statements most accurately describes the efficacy of fluoroquinolones for this patient?
 
  a. Fluoroquinolones have no effect on the prothrombin time.
  b. Fluoroquinolones shorten the prothrombin time.
  c. Fluoroquinolones prolong the prothrombin time.
  d. Fluoroquinolones have an uncertain effect on prothrombin time.

[dreamfighter72]

Answer to Question 1

ANS: D
The most common effect associated with sulfonamides is hypersensitivity, including skin erup-tions, urticaria, pruritus, photosensitivity, periorbital edema, and erythema multiforme.

Answer to Question 2

ANS: C
Quinolones enhance the action of warfarin, so prothrombin time would be prolonged, and close monitoring of prothrombin time (PT) and international normalized ratio (INR) levels is warrant-ed. Levofloxacin used concomitantly with warfarin may cause QT prolongation.

[appyboo]

Both answers were spot on, thank you once again

[dreamfighter72]

Great! Please up vote