A patient who is being started on drug therapy with gemfibrozil ...

[james9437]

A patient who is being started on drug therapy with gemfibrozil (Lopid) is also receiving oral an-ticoagulant therapy with warfarin (Coumadin). Which of the following statements describes the effect of gemfibrozil on anticoagulant therapy?
 
  a. It is likely to decrease the anticoagulant effect.
  b. It is likely to increase the anticoagulant effect.
  c. Its use is contraindicated if the patient is being anticoagulated.
  d. It has no effect on the action of the anticoagulant.

Question 2

A patient currently taking fenofibrate complains of nausea, vomiting, and dyspepsia. What is the correct interpretation of these symptoms by the health care provider?
 
  a. The patient is allergic to the drug.
  b. The patient is experiencing severe adverse effects of the drug.
  c. The patient is experiencing common adverse effects of the drug.
  d. The patient is nonadherent with drug therapy.

[chreslie]

Answer to Question 1

ANS: B
The action of warfarin is enhanced in the presence of gemfibrozil and fenofibrate.

Answer to Question 2

ANS: C
The most common adverse effects are gastrointestinal (GI)-related and include epigastric dis-tress, nausea and vomiting, dyspepsia, flatulence, and constipation. Flulike symptoms, including myopathy and arthralgias, are also common.

[james9437]

TYSM

[momolu]

Excellent