Author Question: Which of the following drugs used to manage lower gastrointestinal disorders increase the risk of ... (Read 65 times)

rmenurse · **on:** Jul 23, 2018

Which of the following drugs used to manage lower gastrointestinal disorders increase the risk of bleeding when administered to clients taking warfarin (Coumadin)? Select all that apply.

A) Mesalamine (Asacol)
B) Bisacodyl (Dulcolax)
C) Psyllium (Metamucil)
D) Polyethylene glycol (MiraLAX)
E) Olsalazine (Dipentum)

Question 2

A nurse is preparing to administer sulfasalazine (Azulfidine) to a client with inflammatory bowel disease.

The nurse checks the client's medical record for a history of hypersensitivities, understanding that the drug should not be administered to a client with hypersensitivity to which of the following drugs? Select all that apply.

A) Enalapril (Vasotec)
B) Doxycycline (Vibramycin)
C) Azithromycin (Zithromax)
D) Sulfamethoxazole/trimethoprim (Bactrim)

tashiedavis420 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Ans: A, E
Feedback:
Aminosalicylates, like mesalamine (Asacol) and olsalazine (Dipentum), can increase the risk of bleeding in clients taking warfarin (Coumadin).

Answer to Question 2

Ans: D
Feedback:
Sulfasalazine (Azulfidine) is an aminosalicylate. The use of aminosalicylates is contraindicated in clients with hypersensitivity to sulfonamides and sulfites, which includes sulfamethoxazole/trimethoprim (Bactrim).