Answer to Question 1
4
Rationale 1: The risk of side effects does not increase because of chronic disease; it is doserelated.
Rationale 2: The risk of side effects does not increase because of chronic disease; it is doserelated.
Rationale 3: Symptoms of the cancer are separate from side effects of estrogen use as treatment.
Rationale 4: Estrogens are used to reduce unpleasant symptoms associated with menopause and to treat certain types of cancers. Higher doses are used for these conditions; thus, more side effects are observed.
Global Rationale: Estrogens are used to reduce unpleasant symptoms associated with menopause and to treat certain types of cancers. Higher doses are used for these conditions; thus, more side effects are observed. The risk of side effects does not increase because of chronic disease; it is doserelated. Symptoms of the cancer are separate from side effects of estrogen use as treatment.
Answer to Question 2
2, 3, 5
Rationale 1: Endometrial cancer is not a risk if progesterone is added to HRT.
Rationale 2: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their healthcare provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism.
Rationale 3: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their healthcare provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism.
Rationale 4:Breast cancer is incorrect because there is some data that suggests HRT helps prevent some breast cancers.
Rationale 5: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their healthcare provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism.
Global Rationale: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their healthcare provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism. Endometrial cancer is incorrect because it is not a risk if progesterone is added to HRT. Breast cancer is incorrect because there is some data that suggests HRT helps prevent some breast cancers.