Author Question: A nurse is preparing to administer an antineoplastic medication. Upon reviewing the medication ... (Read 148 times)

cmoore54 · **on:** Jul 23, 2018

A nurse is preparing to administer an antineoplastic medication. Upon reviewing the medication administration record,the nurse does not see a medication to prevent nausea and vomiting. Which group of medications is used for this purpose?

1. Analgesics
2. Serotonin receptor antagonists
3. Hematopoietic drugs
4. Alkylating drugs

Question 2

The nurse is caring for a group of clients who are receiving chemotherapy. The nurse is preparing to administer the medications. Which medications does the nurse correctly identify as alkylating agents?(Select all that apply.)

1. Cisplatin (Platinol)
2. Cyclophosphamide (Cytoxan)
3. Chlorambucil (Leukeran)
4. Estramustine (Emcyt)
5. Interferon alfa-2 (Roferon A)

princessflame2016 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

2

Rationale 1:Analgesics are used for pain.
Rationale 2:Serotonin receptor antagonists are antiemetics.
Rationale 3:Hematopoietic drugs are used to assist with blood abnormalities of cancer chemotherapy.
Rationale 4:Alkylating drugs are a type of antineoplastic medications.

Global Rationale: Chemotherapy-induced nausea and vomiting can be debilitating for patients. Antineoplastics are classified as their emetogenic potential and those with the highest potential require adjunctive therapy with antiemetics. The most effective drugs used for this purpose are in a class called serotonin receptor antagonists.

Answer to Question 2

1, 2, 3, 4

Rationale 1: Cisplatin (Platinol) is an alkylating agent.
Rationale 2: Cyclophosphamide (Cytoxan) is an alkylating agent.
Rationale 3: Chlorambucil (Leukeran) is an alkylating agent.
Rationale 4: Estramustine (Emcyt) is an alkylating agent.
Rationale 5:Interferon alfa-2 (Roferon A) is a biologic response modifier used to treat hairy cell leukemia and Kaposi sarcoma.

Global Rationale: Cisplatin (Platinol), cyclophosphamide (Cytoxan), chlorambucil (Leukeran), and estramustine (Emcyt) are all alkylating agents. Interferon alfa-2 (Roferon A) is a biologic response modifier used to treat hairy cell leukemia and Kaposi sarcoma.