Author Question: A patient with a severe systemic fungal infection will be treated with amphotericin B (Fungizone). ... (Read 108 times)

vHAUNG6011 · **on:** Jul 23, 2018

A patient with a severe systemic fungal infection will be treated with amphotericin B (Fungizone). What nursing interventions are required?

1. Administer the medication by IV push.
2. Give acetaminophen before giving the amphotericin B (Fungizone).
3. Review BUN level.
4. Give corticosteroids 1 hour after infusion is completed.
5. Monitor for gastrointestinal bleeding.

Question 2

The nurse does medication education for the client with histoplasmosis who receives ketoconazole (Nizoral). The nurse evaluates that learning has occurred when the client makes which statement?

1. I cannot take this medication longer than 10 days.
2. I could develop resistance to this medication if I take it too often.
3. I could develop nausea, vomiting, and abdominal pain with this medication.
4. I can't take my diabetes medicine with this drug.

izzat · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

1,2,3
Rationale 1: This medication should be infused slowly to avoid cardiovascular collapse.
Rationale 2: Giving acetaminophen prior to the infusion may decrease risk of hypersensitivity reaction.
Rationale 3: The drug should be withheld if the BUN exceeds 40 g/dL.
Rationale 4: Corticosteroid administration should be part of pre-administration preparation.
Rationale 5: Gastrointestinal bleeding is not a concern.

Global Rationale: This medication should be infused slowly to avoid cardiovascular collapse. Giving acetaminophen prior to the infusion may decrease risk of hypersensitivity reaction. The drug should be withheld if the BUN exceeds 40 g/dL. Corticosteroid administration should be part of pre-administration preparation. Gastrointestinal bleeding is not a concern.

Answer to Question 2

3
Rationale 1: Ketoconazole (Nizoral) is often used for longer than 10 days.
Rationale 2: Organisms, not people, develop resistance; this is not a likely occurrence anyway.
Rationale 3: Nausea, vomiting, and abdominal pain are common side effects of ketoconazole (Nizoral).
Rationale 4: The azole antifungals may affect glycemic control in diabetic clients. There is no indication to stop medications.
Global Rationale: Nausea, vomiting, and abdominal pain are common side effects of ketoconazole (Nizoral). Ketoconazole (Nizoral) is often used for longer than 10 days. Organisms, not people, develop resistance; this is not a likely occurrence anyway. The azole antifungals may affect glycemic control in diabetic clients. There is no indication to stop medications.