Answer to Question 1
A
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Amphotericin B binds to ergosterol and forms holes in the membrane, causing leakage of fungal cell contents and lysis of the cell. The azole drugs bind to an enzyme that is required for synthesis of ergosterol. This action causes production of a defective cell membrane, which allows leakage of intracellular contents and destruction of the cell. Echinocandins disrupt fungal cell walls rather than fungal cell membranes. They inhibit glycan synthetase, an enzyme required for synthesis of glucan.
Answer to Question 2
B
Feedback:
Eszopiclone (Lunesta) is the first oral nonbenzodiazepine hypnotic to receive FDA approval for long-term use (12 months).
Respiratory Assistive Devices, Patient Using a Peak Flow Meter
Scheduling patient appointments by telephone.
Disorders of the Urinary System
Fungal Pathogens
HIV cycle in an infected cell: (a) latent infection; (b) active infection.
Plasmodium parasites (arrow) attacking and infecting red blood cells. Infection by Plasmodium causes