Answer to Question 1
ANS: C
Salmon calcitonin is the drug of choice for rapid relief of pain associated with Paget's disease. Alendronate, calcifediol, and NSAIDs are not indicated.
Answer to Question 2
ANS: D
Alendronate can induce hyperparathyroidism in patients with Paget's disease; calcium supplementation can prevent this effect. Giving calcium does not reduce the incidence of atrial fibrillation, maximize bone resorption of calcium, or minimize the risk of esophageal cancer.