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Author Question: Two nurses are discussing theories of drug-receptor interaction. Which statements are true regarding ... (Read 55 times)

jilianpiloj

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on: Jul 23, 2018
Two nurses are discussing theories of drug-receptor interaction. Which statements are true regarding the affinity of a drug and its receptor? (Select all that apply.)
 
  a. Affinity and intrinsic activity are dependent properties.
  b. Affinity refers to the strength of the attraction between a drug and its receptor.
  c. Drugs with high affinity are strongly attracted to their receptors.
  d. Drugs with low affinity are strongly attracted to their receptors.
  e. The affinity of a drug for its receptors is reflected in its potency.

Question 2

Which drugs will not be affected by interpatient variability? (Select all that apply.)
 
  a. Antiseptics applied to the skin to slow bacterial growth
  b. Antacids to help with the discomfort of heartburn
  c. Broad-spectrum antibiotics that are effective against many organisms
  d. Chelating agents that remove metal compounds from the body
  e. Topical analgesics used to treat localized pain


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tashiedavis420

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Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B, C, E
Affinity refers to the strength of the attraction between a drug and its receptor. Drugs with high affinity are strongly attracted to their receptors, and the affinity of a drug and its receptors is reflected in its potency. Affinity and intrinsic activity are independent properties. Drugs with low affinity are weakly attracted to their receptors.

Answer to Question 2

ANS: A, B, D
Antiseptics, antacids, and chelating agents are all receptorless drugs that do not depend on the body's processes for effects; these agents react with other molecules. Broad-spectrum antibiotics and topical analgesics bind with receptors to produce desired effects, and these processes can be influenced by individual patient variables.


jilianpiloj

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Reply #2 on: Jul 23, 2018
Both answers were spot on, thank you once again


tashiedavis420

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Reply #3 on: Jul 23, 2018
Great! Please up vote :D


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