Answer to Question 1
Correct Answer: 6
Rationale: Sodium stibogluconate is the traditional drug of choice for leishmaniasis; however, decades of use have led to near-total resistance in certain strains of Leishmania. The drug must be given parenterally for 4 to 6 weeks.
Global Rationale: Sodium stibogluconate is the traditional drug of choice for leishmaniasis; however, decades of use have led to near-total resistance in certain strains of Leishmania. The drug must be given parenterally for 4 to 6 weeks.
Answer to Question 2
Correct Answer: 2
Rationale 1: Changes in sense of smell should not occur.
Rationale 2: Some patients experience a metallic taste.
Rationale 3: Metallic taste is not a symptom of an allergic response.
Rationale 4: Increasing fluid intake will not alleviate this symptom.
Global Rationale: The most common adverse effects are anorexia, nausea, vomiting, diarrhea, abdominal pain, dizziness, and headache. Dryness of the mouth and an unpleasant metallic taste may be experienced. Sense of smell is not altered. Increasing fluid intake is not indicated. This is an adverse effect, not an allergic response.