Author Question: The nurse would recognize which symptom as a sign of a serious adverse effect in a client taking ... (Read 116 times)

mia · **on:** Jul 23, 2018

The nurse would recognize which symptom as a sign of a serious adverse effect in a client taking amphotericin B?

1. Hypokalemia
2. Leukopenia
3. Hematuria
4. Paresthesia

Question 2

The nurse would question the use of amphotericin B in the client concurrently receiving which medication?

1. Actos
2. Vancomycin
3. Captopril
4. Coumadin

kxciann · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 3
Rationale 1: Although hypokalemia can occur, it is not as significant as another symptom.
Rationale 2: Leukopenia can occur, but is not as serious as another symptom.
Rationale 3: Hematuria is a symptom of nephrotoxicity and possible renal failure.
Rationale 4: Paresthesia is not a symptom of a serious adverse effect of amphotericin B.
Global Rationale: Hematuria is a symptom of nephrotoxicity and possible renal failure. Hypokalemia and leukopenia can occur, but are not as serious as possible renal failure. Paresthesia is not an adverse effect of this drug.

Answer to Question 2

Correct Answer: 2
Rationale 1: Actos is used to treat type II diabetes, and is not contraindicated for concurrent use of amphotericin B.
Rationale 2: Drug interactions with amphotericin B focus on worsening two of its potentially serious adverse effects: nephrotoxicity and hypokalemia. For example, concurrent therapy with aminoglycosides, cyclosporine, vancomycin, carboplatin, and furosemide is not recommended.
Rationale 3: Captopril is not contraindicated for concurrent use of amphotericin B.
Rationale 4: Coumadin is not contraindicated for concurrent use of amphotericin B.
Global Rationale: Drug interactions with amphotericin B focus on worsening two of its potentially serious adverse effects: nephrotoxicity and hypokalemia. For example, concurrent therapy with aminoglycosides, cyclosporine, vancomycin, carboplatin, and furosemide is not recommended. The other drugs present no contraindication.