A client taking gemfibrozil (Lopid) and rosuvastatin (Crestor) ...

[jc611]

A client taking gemfibrozil (Lopid) and rosuvastatin (Crestor) reports muscle and joint pain. The nurse's response is based on an interpretation that this complaint might indicate which manifestation?
 
  1. Hepatic injury
  2. Peripheral neuropathy
  3. Myopathy
  4. An inflammatory response

Question 2

The nurse is assigned to care for a client who is prescribed cholestyramine (Questran). To maintain safety for this client relative to potential effects of this drug, the nurse should monitor which laboratory test?
 
  1. Serum glucose
  2. Serum transaminases
  3. Neutrophil count
  4. Serum potassium level

[essyface1]

Answer to Question 1

Correct Answer: 3
Rationale 1: Hepatic injury is a risk associated with these drugs, but the symptom pattern does not indicate damage to the liver.
Rationale 2: Joint pain is not a manifestation of peripheral nerve damage.
Rationale 3: The risk of myopathy is increased in clients taking both a fibrate and a statin drug for hyperlipidemia.
Rationale 4: The mechanism by which statin and fibrate drugs produce myopathy is unknown.
Global Rationale: The risk of myopathy is increased in clients taking both a fibrate and a statin drug for hyperlipidemia. Hepatic injury is a risk associated with these drugs, but the symptom pattern does not indicate damage to the liver. Joint pain is not a manifestation of peripheral nerve damage. The mechanism by which statin and fibrate drugs produce myopathy is unknown.

Answer to Question 2

Correct Answer: 2
Rationale 1: Glucose metabolism is not affected by cholestyramine (Questran).
Rationale 2: Unlike statin drugs, bile acid sequestrants do not carry a risk of hepatic injury.
Rationale 3: Cholestyramine (Questran) does not affect neutrophil production.
Rationale 4: Potassium is not affected by cholestyramine (Questran).
Global Rationale: Unlike statin drugs, bile acid sequestrants do not carry a risk of hepatic injury. Glucose metabolism is not affected by cholestyramine (Questran). Cholestyramine (Questran) does not affect neutrophil production. Potassium is not affected by cholestyramine (Questran).

[jc611]

Both answers were spot on, thank you once again

[essyface1]

Great! Please up vote