Author Question: A nurse who provides care to older adult clients must be aware that which factors may increase the ... (Read 24 times)

Brittanyd9008 · **on:** Jul 23, 2018

A nurse who provides care to older adult clients must be aware that which factors may increase the risk for adverse drug reactions in this population?

1. Longevity results in increased risk for illnesses, which may require multiple medications.
2. Many older clients will use over-the-counter medications to treat common symptoms such as constipation or joint pain in addition to prescription drugs.
3. Older clients may see several health care specialists.
4. The rate of absorption in older clients is unpredictable.
5. Increased volume of total body water results in an increase in concentrations of drugs in the blood.

Question 2

The nurse recognizes that which physiological changes may have what effects on medication responses?

1. Decreased production of serum albumin may result in toxic levels of highly protein-bound drugs.
2. Declining efficiency of the bloodbrain barrier may result in increased central nervous system symptoms.
3. Decreased contractility of the heart may result in decreased distribution of drugs.
4. Decreased gastric pH may result in decreased absorption.
5. Decreased body fat may result in decreased absorption of fat-soluble drugs.

vish98 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 1,2,3
Rationale 1: Longevity inevitably leads to increased illnesses, which in turn necessitate the use of multiple medications, which may result in adverse reactions.
Rationale 2: When a client takes over-the-counter drugs in conjunction with prescribed medication, polypharmacy may occur, resulting in adverse reactions.
Rationale 3: Adverse reactions may occur when multiple health providers prescribe medications.
Rationale 4: The rate of absorption is predictable and would not cause an adverse reaction.
Rationale 5: The decreased volume of total body water may lead to higher concentrations of drugs in the serum.
Global Rationale: Longevity inevitably leads to increased illnesses, which in turn necessitate the use of multiple medications, which may result in adverse reactions. When a client takes over-the-counter drugs in conjunction with prescribed medication, polypharmacy may occur, resulting in adverse reactions. Adverse reactions may occur when multiple health providers prescribe medications. The rate of absorption is predictable and would not cause an adverse reaction. The decreased volume of total body water may lead to higher concentrations of drugs in the serum.

Answer to Question 2

Correct Answer: 1,2,3
Rationale 1: Decreased production of serum albumin in the older client may produce toxic levels of highly protein-bound drugs.
Rationale 2: Declining efficiency of the bloodbrain barrier may result in more substances crossing the bloodbrain barrier, resulting in increased central nervous system symptoms.
Rationale 3: Decreased contractility of the heart may decrease the distribution of drugs.
Rationale 4: Gastric pH is increased in the older client, resulting in medications that require high levels of acid to take longer to be absorbed.
Rationale 5: Body fat is increased in the older client, resulting in increased absorption of fat-soluble drugs.
Global Rationale: Decreased production of serum albumin in the older client may produce toxic levels of highly protein-bound drugs. Declining efficiency of the bloodbrain barrier may result in more substances crossing the bloodbrain barrier, resulting in increased central nervous system symptoms. Decreased contractility of the heart may decrease the distribution of drugs. Gastric pH is increased in the older client, resulting in medications that require high levels of acid to take longer to be absorbed. Body fat is increased in the older client, resulting in increased absorption of fat-soluble drugs.