Answer to Question 1
Correct Answer: 1,2,3
Rationale 1: Longevity inevitably leads to increased illnesses, which in turn necessitate the use of multiple medications, which may result in adverse reactions.
Rationale 2: When a client takes over-the-counter drugs in conjunction with prescribed medication, polypharmacy may occur, resulting in adverse reactions.
Rationale 3: Adverse reactions may occur when multiple health providers prescribe medications.
Rationale 4: The rate of absorption is predictable and would not cause an adverse reaction.
Rationale 5: The decreased volume of total body water may lead to higher concentrations of drugs in the serum.
Global Rationale: Longevity inevitably leads to increased illnesses, which in turn necessitate the use of multiple medications, which may result in adverse reactions. When a client takes over-the-counter drugs in conjunction with prescribed medication, polypharmacy may occur, resulting in adverse reactions. Adverse reactions may occur when multiple health providers prescribe medications. The rate of absorption is predictable and would not cause an adverse reaction. The decreased volume of total body water may lead to higher concentrations of drugs in the serum.
Answer to Question 2
Correct Answer: 1,2,3
Rationale 1: Decreased production of serum albumin in the older client may produce toxic levels of highly protein-bound drugs.
Rationale 2: Declining efficiency of the bloodbrain barrier may result in more substances crossing the bloodbrain barrier, resulting in increased central nervous system symptoms.
Rationale 3: Decreased contractility of the heart may decrease the distribution of drugs.
Rationale 4: Gastric pH is increased in the older client, resulting in medications that require high levels of acid to take longer to be absorbed.
Rationale 5: Body fat is increased in the older client, resulting in increased absorption of fat-soluble drugs.
Global Rationale: Decreased production of serum albumin in the older client may produce toxic levels of highly protein-bound drugs. Declining efficiency of the bloodbrain barrier may result in more substances crossing the bloodbrain barrier, resulting in increased central nervous system symptoms. Decreased contractility of the heart may decrease the distribution of drugs. Gastric pH is increased in the older client, resulting in medications that require high levels of acid to take longer to be absorbed. Body fat is increased in the older client, resulting in increased absorption of fat-soluble drugs.