An infant recently prescribed the anti-infective gentamicin is ...

[PhilipSeeMore]

An infant recently prescribed the anti-infective gentamicin is brought to the emergency department with oliguria, hematuria, cloudy urine, and fever. Which diagnosis would the nurse anticipate for this infant based on the assessment findings?
 
  1. Respiratory distress syndrome
  2. Gasping syndrome
  3. Nephrotoxicity
  4. Neurotoxicity

Question 2

Which factor would lead to the dilution of the drug furosemide (Lasix) in the newborn?
 
  1. The higher proportion of fat to water dilutes water-soluble drugs.
  2. There is no dilution of the drug in pediatric clients.
  3. The lower proportion of water to fat dilutes water-soluble drugs.
  4. The higher proportion of water to fat dilutes water-soluble drugs.

[TheNamesImani]

Answer to Question 1

Correct Answer: 3
Rationale 1: Respiratory distress syndrome is a respiratory problem seen in young children.
Rationale 2: Gasping syndrome is a problem with metabolism, not excretion, in infants.
Rationale 3: Nephrotoxicity is the diagnosis the nurse would anticipate because of the infant's immature renal system and inability to excrete drugs adequately.
Rationale 4: Neurotoxicity is a problem with the nervous system.
Global Rationale: Nephrotoxicity is the diagnosis the nurse would anticipate because of the infant's immature renal system and inability to excrete drugs adequately. Respiratory distress syndrome is a respiratory problem seen in young children. Gasping syndrome is a problem with metabolism, not excretion, in infants. Neurotoxicity is a problem with the nervous system.

Answer to Question 2

Correct Answer: 4
Rationale 1: The proportion of water to fat is higher in the newborn.
Rationale 2: The high water-to-fat ratio in the newborn dilutes furosemide.
Rationale 3: The proportion of water to fat is higher in the newborn.
Rationale 4: The newborn's weight is 80 water. The high proportion of water to fat dilutes water-soluble drugs.
Global Rationale: The newborn's weight is 80 water. The high proportion of water to fat dilutes water-soluble drugs. The proportion of water to fat is higher in the newborn. The high water-to-fat ratio in the newborn dilutes furosemide.

[PhilipSeeMore]

TYSM

[tkempin]

Excellent