Author Question: A prescriber is adjusting doses of a particular drug. A nurse understands that the most accurate ... (Read 9 times)

captainjonesify · **on:** Jul 23, 2018

A prescriber is adjusting doses of a particular drug. A nurse understands that the most accurate dose determination can be calculated based on the

a. drug's pharmacokinetics.
b. patient's gender.
c. patient's basal metabolic index (BMI).
d. patient's body surface area.

Question 2

A nurse is providing patient education to a group of women regarding the variability of drug absorption. The nurse is evaluating learning in the group and asks how genetics may influence drug response.

Which statement made by a member of the group would indicate a need for further teaching?
a. Prior to 1997, drug companies did many fewer studies involving drugs and women.
b. Certain opioid analgesics are much more effective in women than in men.
c. Men and women respond differently to drugs, but little is known about how and why.
d. Alcohol is metabolized quicker by women than by men.

bblaney · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: D
Body surface area is the most accurate method of dose determination and/or adjustment.
Pharmacokinetics involves absorption, distribution, metabolism, and excretion, but it is not specific to drug dosing.
A patient's gender is not the most accurate method of dosing, because each individual is different.
The BMI is an indication of weight and height proportions, not an accurate determinant of drug dosing.

Answer to Question 2

ANS: D
Women metabolize alcohol at a much slower rate than men do; further teaching is required.
Prior to 1997 drug companies did many fewer studies involving drugs and women; no further education is required. Studies have increased since 1997 to examine the effects of drugs on women as they relate to pregnancy and adverse effects on the fetus.
Certain opioid analgesics are much more effective in women than in men' no further education is required.
Men and women respond differently to drugs; no further education is required.