Author Question: The nurse is caring for a group of missionaries who have just returned from a region where malaria ... (Read 15 times)

lilldybug07 · **on:** Jul 23, 2018

The nurse is caring for a group of missionaries who have just returned from a region where malaria is endemic. For which patients, who are undergoing treatment for an ongoing attack of malaria, would mefloquine (Lariam) be contraindicated?

(Select all that apply.)
a. Patients with renal insufficiency
b. Patients with epilepsy
c. Patients with osteoarthritis
d. Patients with a psychiatric disorder
e. Patients with type 2 diabetes

Question 2

The nurse is caring for a patient with severe symptomatic intestinal amebiasis who has just completed a 10-day course of metronidazole (Flagyl). Which medication would the nurse expect to be ordered for the patient?

a. Pentamidine (Pentam)
b. Iodoquinol (Yodoxin)
c. Atovaquone (Mepron)
d. Nitazoxanide (Alinia)

yasmina · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: B, D
Mefloquine is contraindicated in patients who have a history of epilepsy and psychiatric disorders.
Mefloquine is not contraindicated in patients with renal insufficiency, osteoarthritis, or type 2 diabetes.

Answer to Question 2

ANS: B
The metronidazole concentration in the stomach remains low, therefore some amoebas survive. Using iodoquinol as the subsequent drug achieves high concentrations, killing the remaining amoebas.
Pentamidine, atovaquone, and nitazoxanide are indicated for treatment of diseases other than amebiasis.