Author Question: The nurse understands that the priority benefit of enteric-coated aspirin preparations is to prevent ... (Read 33 times)

asmith134 · **on:** Jul 23, 2018

The nurse understands that the priority benefit of enteric-coated aspirin preparations is to prevent

a. Reye's syndrome.
b. salicylism.
c. gastritis.
d. acid-base imbalance.

Question 2

When administering aspirin to a patient with a history of peptic ulcer disease, the nurse may anticipate administering which drug(s) for prophylaxis against aspirin-induced ulcers? (Select all that apply.)

a. Misoprostol (Cytotec)
b. Ranitidine (Zantac)
c. Omeprazole (Prilosec)
d. Lansoprazole (Prevacid)
e. Antacids

duy1981999 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: C
The enteric coating prevents the aspirin from dissolving in the stomach and allows it to dissolve in the duodenum, thus reducing gastric irritation.
Reye's syndrome remains a risk despite the tablet preparation. The properties of aspirin, regardless of its preparation, can lead to Reye's syndrome.
Salicylism remains a risk despite tablet preparation, because salicylism is the result of aspirin overdose, which still can occur with absorption in the duodenum.
Acid-base imbalance is unlikely to occur unless aspirin is taken in large amounts; the type of tablet preparation would have no effect on this.

Answer to Question 2

ANS: A, C, D
Misoprostol stimulates prostaglandin synthesis and is used for prophylaxis in patients taking aspirin. Omeprazole and lansoprazole are proton pump inhibitors that can be used to prevent and treat aspirin-induced ulcers, because proton pump inhibitors suppress gastric acid.
Ranitidine and antacids are not indicated for the prevention and treatment of aspirin-induced ulcers.