The provider has ordered amoxicillin with clavulanate (Augmentin) ...

[cherise1989]

The provider has ordered amoxicillin with clavulanate (Augmentin) for a child who has otitis media. The child's parent asks why this drug is necessary when amoxicillin is less expensive.
 
  The nurse will explain that clavulanate is added to amoxicillin because it
  a. binds with albumin to increase the amount of available amoxicillin.
  b. broadens the spectrum of amoxicillin by inhibiting bacterial enzymes.
  c. inhibits hepatic blood flow, leading to increased serum drug levels of amoxicillin.
  d. inhibits the excretion of amoxicillin by interfering with renal function.

Question 2

A young adult female patient who takes a combination oral contraceptive (OCP) will begin taking an antibiotic. When teaching the patient about this medication, the nurse will
 
  a. recommend using a backup method of contraception.
  b. suggest that she switch to an injectable form of contraception.
  c. tell her that the antibiotic is less effective if she is taking OCPs.
  d. tell her the antibiotic has a greater risk for toxicity while taking OCPs.

[tandmlomax84]

Answer to Question 1

ANS: B
Clavulanate is a bacterial enzyme inhibitor, specifically beta-lactamase, which inactivates amoxicillin. When added to amoxicillin, it broadens the antibacterial spectrum.

Answer to Question 2

ANS: A
Gut bacteria are necessary to hydrolyze estrogen conjugates into free estrogens. Concurrent antibiotic administration can alter these bacteria and prevent the optimal absorption and effectiveness of OCPs. A backup contraceptive method is recommended.

[cherise1989]

TYSM

[Bigfoot1984]

Gracias!