This topic contains a solution. Click here to go to the answer

Author Question: A patient has been taking a drug that has a protein-binding effect of 75. The provider adds a new ... (Read 106 times)

Alygatorr01285

  • Hero Member
  • *****
  • Posts: 564
A patient has been taking a drug that has a protein-binding effect of 75. The provider adds a new medication that has a protein-binding effect of 90. The nurse will expect
 
  a. decreased drug effects of the first drug.
  b. decreased therapeutic range of the first drug.
  c. increased drug effects of the first drug.
  d. increased therapeutic range of the first drug.

Question 2

The nurse is administering two drugs to a patient and learns that both drugs are highly protein-bound. The nurse may expect
 
  a. decreased bioavailability of both drugs.
  b. decreased drug effects.
  c. decreased drug interactions.
  d. increased risk of adverse effects.



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

vickybb89

  • Sr. Member
  • ****
  • Posts: 347
Answer to Question 1

ANS: C
Adding another highly protein-bound drug will displace the first drug from protein-binding sites and release more free drug increasing the drug's effects. This does not alter the therapeutic range, which is the serum level between drug effectiveness and toxicity.

Answer to Question 2

ANS: D
Two drugs that are highly protein-bound will compete for protein-binding sites, leaving more free drug in circulation and an increased risk of adverse effects as well as increased bioavailability, increased drug effects, and increased drug interactions.




Alygatorr01285

  • Member
  • Posts: 564
Reply 2 on: Jul 23, 2018
Excellent


bigcheese9

  • Member
  • Posts: 333
Reply 3 on: Yesterday
Great answer, keep it coming :)

 

Did you know?

After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.

Did you know?

Tobacco depletes the body of vitamins A, C, and E, which can result in any of the following: dry hair, dry skin, dry eyes, poor growth, night blindness, abscesses, insomnia, fatigue, reproductive system problems, sinusitis, pneumonia, frequent respiratory problems, skin disorders, weight loss, rickets, osteomalacia, nervousness, muscle spasms, leg cramps, extremity numbness, bone malformations, decayed teeth, difficulty in walking, irritability, restlessness, profuse sweating, increased uric acid (gout), joint damage, damaged red blood cells, destruction of nerves, infertility, miscarriage, and many types of cancer.

Did you know?

Most women experience menopause in their 50s. However, in 1994, an Italian woman gave birth to a baby boy when she was 61 years old.

Did you know?

The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.

Did you know?

Autoimmune diseases occur when the immune system destroys its own healthy tissues. When this occurs, white blood cells cannot distinguish between pathogens and normal cells.

For a complete list of videos, visit our video library