A child ingests a parent's aspirin tablets, and the prescriber ...

[Charlie]

A child ingests a parent's aspirin tablets, and the prescriber orders sodium bicarbonate to block the toxic effects of the aspirin. The nurse caring for this patient knows that sodium bicarbonate is effective against the aspirin because it:
 
  a. accelerates its passage through the intes-tine.
  b. alters urinary pH to enhance renal excre-tion.
  c. induces CYP isoenzymes to increase drug metabolism.
  d. raises the pH of the interstitial fluid to fa-cilitate passage out of the cells.

Question 2

A patient with type 1 diabetes recently became pregnant. The nurse plans a blood glucose testing schedule for her. What is the recommended monitoring schedule?
 
  a. Before each meal and before bed
  b. In the morning for a fasting level and at 4:00 PM for the peak level
  c. Six or seven times a day
  d. Three times a day, along with urine glu-cose testing

[brbarasa]

Answer to Question 1

D
Sodium bicarbonate increases the pH of interstitial fluid and plasma, allowing the acidic aspirin ions to move outside the cells and thus removing them from the site where they have toxic ef-fects. It does not have laxative effects and does not alter the rate of passage through the gut. It is not a CYP isoenzyme inducer and therefore has no effect on drug metabolism. It does not alter renal excretion of aspirin.

Answer to Question 2

C
A pregnant patient with type 1 diabetes must have frequent blood sugar monitoring (eg, six or seven times a day) to manage both the patient and the fetus so that no teratogenic effects occur. Monitoring the blood sugar level before meals and at bedtime is not significant enough to pro-vide the necessary glycemic control. Morning and 4:00 PM monitoring is not enough to provide glycemic control. Urine glucose testing is not sensitive enough to aid glycemic control, and monitoring three times a day is not enough.

[Charlie]

Wow, this really help

[bitingbit]

Thanks for the timely response, appreciate it