Author Question: A patient who has received a heart transplant is taking cyclosporine. The patient is found to have a ... (Read 36 times)

kaid0807 · **on:** Jul 23, 2018

A patient who has received a heart transplant is taking cyclosporine. The patient is found to have a systemic Aspergillus infection. What drug would the nurse question if ordered for this patient?

A) Terbinafine
B) Posaconazole
C) Itraconazole
D) Ketoconazole

Question 2

The nurse is caring for an 8-year-old clinic patient who takes imipramine. The nurse assesses the patient who does not have a history for or signs of depression, so the nurse suspects this drug was prescribed as treatment for what?

A) Enuresis
B) Obsessive compulsive disorder (OCD)
C) Peripheral neuropathy
D) Panic disorder

juicepod · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

D
Feedback:
Ketoconzaole and fluconazole strongly inhibit the cytochrome P450 (CYP450) enzyme system in the liver and is associated with many drugdrug interactions such as increased serum levels of the following agents: cyclosporine, digoxin, oral hypoglycemics, warfarin, oral anticoagulants, and phenytoin. There is no known drug interaction between cyclosporins and terbinafine, posaconazole, or itraconazole.

Answer to Question 2

A
Feedback:
One of the indications for use of the drug imipramine is enuresis in children older than 6 years. Imipramine is not indicated for the treatment of OCD, peripheral neuropathy, or panic disorder.