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Author Question: A patient who has received a heart transplant has been given an order for drugs that block T cell ... (Read 36 times)

Zoey63294

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A patient who has received a heart transplant has been given an order for drugs that block T cell activity. What is the rationale behind this order?
 
  A) To manufacture antibodies to the foreign proteins
  B) To stimulate wound healing
  C) To combine with a complement to cause a massive inflammatory reaction
  D) To prevent an inflammatory reaction against the transplanted heart

Question 2

After administering digoxin, what assessment finding would indicate to the nurse that the drug was having the desired effect?
 
  A) Increased heart size
  B) Increased urinary output
  C) Decreased respiratory rate
  D) Increased heart rate



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emsimon14

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Answer to Question 1

D
Feedback:
Effector or cytotoxic T cells are aggressive against nonself-cells, releasing cytokines that can either directly destroy a foreign cell or mark it for aggressive destruction. If the transplanted organ is attacked by cytokines, it will be destroyed, referred to as organ rejection. As a result, inhibition of these killer T cells is essential to continued organ function in the transplanted organ. Blocking T cells would not manufacture antibodies, stimulate wound healing, or trigger a massive inflammatory response.

Answer to Question 2

B
Feedback:
As cardiac output improves, so does urinary output due to increased renal perfusion. Respiratory rate and heart size would not be impacted by the drug, although ventricular hypertrophy is a common finding in patients with heart failure. Heart rate would decrease as the force of contraction increases, ejecting more blood with each contraction.





 

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