A homeless man who is well known to care providers at the local hospital has been admitted to the emergency department after having a seizure outside a mall.
The man is known to be a heavy alcohol user and is malnourished with a very low body mass index. How are this patient's characteristics likely to influence possible treatment with phenytoin?
A) The patient will require oral phenytoin rather than intravenous administration.
B) Phenytoin is contraindicated within 48 hours of alcohol use due to the possibility of paradoxical effects.
C) The patient's heavy alcohol use will compete with phenytoin for binding sites and he will require a higher-than-normal dose.
D) The patient's protein deficit will likely increase the levels of the free drug in his blood.
Question 2
A patient comes to the clinic asking for help to quit drinking alcohol. She has a 21-year history of heavy drinking and is worried about developing cirrhosis of the liver. The patient agrees to take disulfiram (Antabuse).
The nurse will teach the patient that the combination of alcohol and Antabuse will cause which of the following?
A) Bradycardia
B) Diarrhea
C) Nausea
D) Slight headache
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