Author Question: The primary care NP is reviewing evidence-based recommendations about the off-label use of a ... (Read 60 times)

sdfghj

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The primary care NP is reviewing evidence-based recommendations about the off-label use of a particular drug. Which recommendation should influence the NP's decision about prescribing the medication?
 
  a. Data from randomized, experimental studies
  b. Patient reports about effectiveness of the drug for this purpose
  c. Pharmaceutical company reports using anecdotal evidence
  d. Endorsement of this use by a leading practitioner in the field

Question 2

A patient is in the clinic for an annual physical examination. The primary care NP obtains a medication history and learns that the patient is taking a B-blocker and nitroglycerin.
 
  The NP orders laboratory tests, performs a physical examination, and performs a review of systems. Which finding may warrant discontinuation of the -blocker in this patient? a. Increased triglycerides
  b. Decreased exercise tolerance
  c. Wheezing, dyspnea, and cough
  d. Nausea, vomiting, and anorexia



Pswine

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Answer to Question 1

A
Randomized, experimental studies yield the best data about use of medications. Patient reports carry the least weight because bias can occur and other factors can influence outcomes. Pharmaceutical company reports are biased.

Answer to Question 2

C
B-Blockers may cause bronchospasm in susceptible patients, and discontinuation of the B-blocker may be required. B-Blockers may cause an insignificant increase in serum triglycerides. Exercise intolerance, fatigue, and gastrointestinal side effects are common.



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