Which drug is the cornerstone of treatment for prophylaxis and ...

[NguyenJ]

Which drug is the cornerstone of treatment for prophylaxis and treatment of tuberculosis (TB)?
 
  a. Amphotericin B (Abelcet)
  b. Streptomycin (Streptomycin)
  c. Isoniazid (Nydrazid)
  d. Acyclovir (Zovirax)

Question 2

Which conditions may occur with the administration of broad-spectrum antibiotics over an extended period of time?
 
  a. Cross sensitivity
  b. Immunosuppression
  c. Secondary infection
  d. Immunity

[Sweetkitty24130]

Answer to Question 1

ANS: C
Isoniazid has been the mainstay for years in the treatment and prevention of TB. The mechanism of action of isoniazid is not fully known. Isoniazid appears to disrupt the Mycobacterium tuberculosis cell wall and inhibit replication. Amphotericin B is used in the treatment of fungal infections. Streptomycin is an aminoglycoside used to treat bacterial infections. Acyclovir is used in the treatment of viral infections associated with herpes simplex virus.

Answer to Question 2

ANS: C
Secondary infections, such as oral thrush, genital and anal pruritus, and vaginitis, can occur with prolonged use of broad-spectrum antibiotics. Secondary infections result when normal flora are eliminated, which causes disease-producing microorganisms to multiply. Cross sensitivities develop during repeat exposures, not over a prolonged period. Immunosuppression does not develop over a prolonged interval of administration. Immunity is not produced by exposure to antibiotics.

[NguyenJ]

Excellent

[duy1981999]

TYSM