Which is the best description of when drug interactions occur? ...

[Engineer]

Which is the best description of when drug interactions occur?
 
  a. On administration of toxic dosages of a drug
  b. On an increase in the pharmacodynamics of bound drugs
  c. On the alteration of the effect of one drug by another drug
  d. On increase of drug excretion

Question 2

The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes after administration, the nurse finds the patient agitated and stating that everyone is out to get me. What is the term for this unusual reaction?
 
  a. Desired action
  b. Adverse effect
  c. Idiosyncratic reaction
  d. Allergic reaction

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Answer to Question 1

ANS: C
Drug interactions may be characterized by an increase or decrease in the effectiveness of one or both of the drugs. Toxicity of one drug may or may not affect the metabolism of another one. Drug interactions may result from either increased or decreased pharmacodynamics. Drug interactions may result from either increased or decreased excretion.

Answer to Question 2

ANS: C
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first administered. Patients typically exhibit an overresponsiveness to a medication related to diminished metabolism. These reactions are believed to be related to genetic enzyme deficiencies. Desired actions are expected responses to a medication. Adverse effects are reactions that occur in another system of the body; they are usually predictable. Allergic reactions appear after repeated medication dosages.

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